Over the last years, biology techniques have considerably evolved, whether it be with mass spectrometry protein analysis or multiplex protein analysis and nucleic acids with qPCR, or sequencing… All those techniques have reached sensitivity levels never reached before. In parallel to increased sensitivity, cost per point has become lower for all laboratories, broadening the possibilities and perspectives for all researchers.

However, the collection/extraction of the interest molecules remains quite often underestimated in the process. Precellys homogenizers and lysing kits are recognized in the scientific world as references for molecules’ optimal extraction, ensuring an ever-higher quality of analysis. Here is a selection of three articles highlighting the importance of qualitative extraction, showing how the versatility and performances of Precellys are crucial to this process.

Preparation of Proliferated Bovine Primary Skeletal Muscle Cells for Bottom-Up Proteomics by LC-MSMS Analysis

Eva Veiseth-Kent, Vibeke HøstMona E. Pedersen
Part of the Methods in Molecular Biology book series (MIMB, volume 1889)
Published in October 2018

Misleading Westerns: Common Quantification Mistakes in Western Blot Densitometry and Proposed Corrective Measures

Trent A. J. Butler, Jonathan W. Paul, Eng-Cheng Chan, Roger Smith, and Jorge M. Tolosa.
Published in 21 January 2019

MicroRNA Transcriptome Profiling in Heart of Trypanosoma cruzi-Infected Mice

Ludmila Rodrigues Pinto Ferreira
Part of the Methods in Molecular Biology book series (MIMB, volume 1955)
Published in June 2015

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