Cryolys cooling option

Efficient cooling for efficient extraction Cryolys is the only patented cooling unit to protect thermo-sensitive molecules during homogenization with Precellys homogenizers. It restricts the heat generation of each sample and maintains their temperature around 10°C. Cryolys delivers higher yield and quality extraction. Easy-handling Thanks to the thermometer probe included with the Cryolys, precise temperature monitoring is possible before, during and after homogenization. The thermo-protection Cryolys unit enables the extraction of stable RNA and native-state proteins. Cold air, -50°C, is sprayed around each tube in order to keep them at a stable temperature of approximately 10°C during homogenization.

The Cryolys is the cooling option for Precellys24 and prevents the degradation of thermo-sensitive molecules like RNA or proteins. Its patented technology maintains a low temperature (0°C- 10°C) before, during and after the grinding process with Precellys. Cryolys technology is based on the use of a compressed air source as a cooling medium. An external compressed air source is linked to the Cryolys which is linked to the Precellys’ lid. The compressed air passes through the internal tank of Cryolys containing either dry ice or liquid nitrogen. The cooled air is then spread inside the Precellys’ lid directly to the tubes. With the appropriate airflow rate, the temperature inside the Precellys’ lid can reach 0°C in 5 minutes and protect thermo-sensitive molecules from degradation

• To access all application notes and full versions, visit the Application Center.Enzyme assay from frozen abdominal krill tissue, Antarctic Krill Group, Dept. Polar Biological Oceanography Alfred Wegener Institute for Polar and Marine Research in the Helmholtz, Association, Am Handelshafen , Bremerhaven, Germany, Animal & Aquaculture science (code: 03712-810-DU063)
• Binding of one lipophilic compound to the Precellys tubes with ceramic beads during tissue homogenization, Songmao Zheng, Justina C. Calamia, Departments of Pharmaceutics, University of Washington, Seattle, WA, USA, Pharmaceutical sciences (code:03712-810-DU067)
• Metabolomic study of the red algae Chondrus crispus, MetaboMER, Metabolomic Platform, FR2424 CNRSUPMC, Station Biologique de Roscoff, Roscoff, France, Animal & Aquaculture science (code: 03712-810-DU068)
• MicroRNA expression profiling of individual rat hypothalamic nuclei, Neuroendocrinologie Moléculaire de la Prise Alimentaire, University of Paris-Sud 11, UMR 8195, Orsay, France and Neuroendocrinologie Moléculaire de la Prise Alimentaire, CNRS, Centre de Neurosciences, Paris-Sud UMR8195, Orsay, France, Biomedical & Health sciences (code: 03712-810-DU074)
• Sample extraction for quantification of mold antigen, Institut für Prävention und Arbeitsmedizin, Institut der Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp Platz, Bochum, Germany, Biomedical & Health sciences (code: 03712-810-DU075)

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