Tissue Homogenizers – Sample preparation - Bertin Instruments
Sample preparation is critical to master molecules extraction from biological samples. Bertin Instruments offers efficient and flexible Precellys tissue homogenizers for grinding any samples prior to analysis.
In most of the sample preparation protocols, one of the first steps is to disrupt your sample with a tissue homogenizer before the extraction of molecules of interest. The Precellys tissue homogenizers provide a full range of fast and reproducible solutions to achieve any type of sample preparation. These products are designed to avoid cross-contamination with optimal tissue grinding or cell disruption.
Sample preparation is critical to obtain the adequate quantity and quality of interest molecules from biological samples.
It is a delicate and time-consuming process. Bertin Instruments offers a range of efficient and flexible Precellys homogenizers based on bead beating technology for grinding samples prior to DNA, RNA and protein analysis. Tissue homogenizers, combined with a dedicated lysing kit, are a lab’s best partner to save time and improve the efficiency of sample preparation protocols.
Particularly, the Precellys Evolution can process four different sizes of tubes and up to 24 tubes simultaneously.
Its flexibility and high efficiency give scientists the ability to prepare any type of soft or hard samples in seconds. The large range of lysing kits, based on different bead materials such as metal, ceramic, glass and garnet beads, make it suitable for multiple biological applications.
Cancer research
Hard tissues such as those from tumors can be particularly difficult to homogenize, and animal models are often used in cancer research. Precellys homogenizer is perfectly adapted to applications of this kind.
Agronomy
Agronomy research into GMO analysis, food allergies and plant studies, often require grounded hard samples such as seeds, roots or frozen food, which are particularly hard to grind.
Forensic
Extremely hard samples such as bone, teeth, and hair are common in forensic laboratories. Popular downstream applications include DNA extraction from bone or teeth and drug extraction from hair.
Pharmacology
Pharmaceutical research starts with lead molecule identification from a natural or artificial model. In either case, the DMPK or animal toxicology models analysis requires the homogenization of tissues.
Environment
Soil and environmental analysis often focus on microbiology studies and pollution impact on wildlife. Microorganisms included in a biological matrix are particularly challenging to lyse.
Microbiology
Microorganism studies are critical as they are used for bio-production and health research. They are difficult to lyse due to their thick cell wall, which makes nucleic acid extraction difficult.
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