A Novel, Selective and Efficacious Nanomolar Pyridopyrazinone Inhibitor of V600EBRAF - Bertin Instruments

    Scientific publications

    A Novel, Selective and Efficacious Nanomolar Pyridopyrazinone Inhibitor of V600EBRAF

    Steven Whittaker1, Delphine Menard2, Ruth Kirk3, Lesley Ogilvie4, Douglas Hedley4, Alfonso Zambon5, Filipa Lopes2, Natasha Preece2, Helen Manne5, Sareena Rana1, Maryou Lambros6, Jorge Reis-Filho7, Richard Marais8, and Caroline J Springer9,*
    Sources: 1Signal Transduction Team, The Institute of Cancer research, 2Gene and Oncogene Targeting Team, The Institute of Cancer research, 3Section of Cell and Molecular Biology, Institute of Cancer research, 4Cancer Therapeutics, Institute of Cancer research, 5Cancer research, UK Centre for Cancer Therapeutics, Institute of Cancer research, 6Institute of Cancer research,, The breakthrough Breast Cancer research, Centre 7Breakthrough Breast Cancer, Institute of Cancer research, 8Signal Transduction Team, Institute of Cancer research, 9Cancer research, UK Centre for Cancer Therapeutics, The Institute of Cancer research,
    Cancer research,OnlineFirst August 31, 2010; doi: 10.1158/0008-5472.CAN-10-1366

    Sample name

    Animal tissues (tumors mice)

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