Drug extraction from brain, muscle rat tissues - Bertin Instruments

    Pharmacology

    Drug extraction from brain, muscle rat tissues

    Sources: PharmOptima, Portage MI, USA

    Context

    PharmOptima focuses on in vivo and in vitro DM&PK and Discovery Services, providing IND & NDAenabling research protocols. High quality DM&PK and Ocular PK research are a part of the laboratory’s daily activities. PharmOptima lab currently uses Precellys to homogenize a variety of animal tissues. In this study, Minilys has been compared with Precellys to homogenize brain and rat muscle.

    Results

    The analyte levels by samples are equivalent. No difference involving the both homogenizers is detectable (See Figure 1).

     

    Figure 1: LC-MS/MS analysis from Precellys and Minilys sample.

    Figure 1: LC-MS/MS analysis from Precellys andMinilys sample.

     

    Muscle tissues in CKmix kit 2mL vial

    Muscle tissues in CKmix kit 2mL vial

     

    Minilys processing

    Minilys processing

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