Human Mitochondrial Thymidine Kinase Is Selectively Inhibited by 3'-Thiourea Derivatives of β-Thymidine: Identification of Residues Crucial for Both Inhibition and Catalytic Activity - Bertin Instruments

    Scientific publications

    Human Mitochondrial Thymidine Kinase Is Selectively Inhibited by 3'-Thiourea Derivatives of β-Thymidine: Identification of Residues Crucial for Both Inhibition and Catalytic Activity

    Jan Balzarini, Ineke Van Daele, Ana Negri, Nicola Solaroli, Anna Karlsson, Sandra Liekens, Federico Gago, and Serge Van Calenbergh
    Sources: Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, Belgium (J.B., S.L.); University of Ghent, Ghent, Belgium (I.V.D., S.V.C.); Departamento de Farmacologia, Universidad de Alcalá, Alcalá de Henares, Madrid, Spain (A.N., F.G.);Karolinska Institute, Huddinge University Hospital, Huddinge, Sweden (N.S., A.K.)
    Molecular Pharmacology, Fast Forward First published on February 20, 2009; DOI: 10.1124/mol.108.0537850026-895X/09/7505-1127-1136$20.00Mol Pharmacol 75:1127-1136, 2009

    Sample name

    Animal tissues (Liver mice)

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