The HSP90 Inhibitor NVP-AUY922 Radiosensitizes by Abrogation of Homologous Recombination Resulting in Mitotic Entry with Unresolved DNA Damage - Bertin Instruments

    Scientific publications

    The HSP90 Inhibitor NVP-AUY922 Radiosensitizes by Abrogation of Homologous Recombination Resulting in Mitotic Entry with Unresolved DNA Damage

    Shane Zaidi1., Martin McLaughlin1*., Shreerang A. Bhide1, Suzanne A. Eccles2, Paul Workman3, Christopher M. Nutting4, Robert A. Huddart5, Kevin J. Harrington1,4
    Sources: 1 Targeted Therapy Team, Institute of Cancer research,, Chester Beatty Laboratories, London, United Kingdom, 2 Tumour Biology and Metastasis Team, Cancer research, UK Cancer Therapeutics Unit, The Institute of Cancer research,, Haddow Laboratories, Sutton, Surrey, United Kingdom, 3 Signal Transduction and Molecular Pharmacology, Team, Cancer research, UK Cancer Therapeutics Unit, The Institute of Cancer research,, Haddow Laboratories, Sutton, Surrey, United Kingdom, 4 The Royal Marsden Hospital, London, United Kingdom, 5 The Royal Marsden Hospital, Sutton, United Kingdom
    The HSP90 Inhibitor NVP-AUY922 Radiosensitizes by Abrogation of HomologousRecombination Resulting in Mitotic Entry with Unresolved DNA Damage. PLoS ONE 7(4): eLife Sciences436. doi:10.1371/journal.pone.00Life Sciences436

    Sample name

    Animal tissues (tumor and liver mice)

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