The role of γ-Secretase Activating Protein, GSAP and imatinib in the regulation of γ-secretase activity and amyloid-β generation. - Bertin Instruments

    Scientific publications

    The role of γ-Secretase Activating Protein, GSAP and imatinib in the regulation of γ-secretase activity and amyloid-β generation.

    Ishrut Hussain1*, Julien Fabrègue1, Laurence Anderes1, Solenne Ousson1#, Frédéric Borlat2, Valérie Eligert1, Sébastien Berger3,Mitko Dimitrov4, Jean-René Alattia4, Patrick C. Fraering4 & Dirk Beher1#.
    Sources: 1Therapeutic Area Neurodegenerative Diseases, Merck Serono S.A., Chemin des Mines 9, 1202 Geneva, Switzerland; 2Protein and Cell Sciences, Merck Serono S.A., Chemin des Mines 9, 1202 Geneva, Switzerland; 3Quantitative Bioanalytics, Merck Serono S.A., Frankfurter Str. 250, D64293 Darmstadt, Germany; 4Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland
    JBC Papers in Press. Published on December 3, 2012 as Manuscript M112.370924 The latest version is at http://www.jbc.org/cgi/doi/10.1074/jbc.M112.370924

    Sample name

    Animal tissues (Brain rat)

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