Histamine is a molecule that plays a major role in local immune responses and acts as a neurotransmitter for the brain, spinal cord, and uterus. An increase in local histamine levels can lead capillaries to become more permeable to leucocytes and some proteins, enabling them to attack pathogens in infected tissues.
Following its discovery in 1910, histamine has been identified as a central player in the pathophysiology of allergy and asthma. To understand the role of histamine in inflammatory reactions it is essential to be able to measure histamine levels accurately.

In this white paper, discover three applications of how Bertin Bioreagent Histamine ELISA kit can be used to detect and quantify histamine in complex biological matrices.
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